Which modifier would indicate a staged procedure during the global period of another procedure?

The appropriate modifier to indicate a staged procedure during the global period of another procedure is Modifier 58. This modifier is used to denote that a procedure was planned or staged at the time of the original procedure and is necessary for clarifying that the follow-up procedure is related to the original surgery.

Modifier 58 informs payers that the staged procedure is not simply an unrelated incident but is part of a coherent treatment plan for a single condition, thereby preventing confusion regarding billing and payment. This modifier is particularly important in circumstances where additional surgical interventions are anticipated as part of the overall management of a patient's condition and helps document the medical necessity of such staged services.

In contrast, other modifiers listed serve different purposes: Modifier 25 indicates that a significant, separately identifiable evaluation and management service was performed on the same day as another procedure. Modifier 22 is used to report increased procedural services when a procedure requires substantially more work than typically required. Modifier 77 refers to the repeat procedure by a different physician or other qualified health care professional. None of these modifiers convey the specific intent of indicating a staged procedure during the global period of another procedure as effectively as Modifier 58 does.